bioeng_admin
2006-07-14 18:40:35
0
49
세미나를 아래와 같이 안내하오니 관심있으신 분들의 많은 참여 바랍니다.
- 아 래 -
1) 제목 : Microfluidic Devices for Continuous Real Time Blood Plasma Separation and
Analysis
2) 연사 : Dr. Sung Yang
3) 소속 : Department of Bioengineering, The Pennsylvania State University,
University Park, PA, USA
4) 일시 : 2006. 7. 14 (Fri) 16:10-17:30
5) 장소 : Room 219, Chung Moon Soul Building (E16)
<Abstract>:
It is well known that that cardiac surgery induces systemic inflammatory responses,
particularly when cardiopulmonary bypass (CPB) procedure is used. These systemic responses are attributed to several factors, including exposure of blood to nonphysiologic surfaces of the heart-lung circuit, ischemia-reperfusion of the involved tissues, surgical trauma and hypothermia. Currently, there is no effective method to prevent this systemic inflammatory response syndrome in patients undergoing CPB. The ability to clinically intervene in inflammation, or even study the inflammatory response to CPB, is limited by the lack of timely measurements of inflammatory responses. Thus, there is a need for a microanalytical system, which can separate blood plasma from whole blood and measure the concentration of the clinically relevant proteins in continuous, real time while the surgery is proceeding.
The goal of this study was to achieve core technologies for the development of a microanalytical system, which can separate blood plasma from blood and measure inflammatory responses in continuous, real time while cardiac surgery is operating. Thus, two independent microfluidic devices are introduced throughout the talk. One is a microfluidic device for continuous, real time blood plasma separation from blood. Second is a microfluidic device for continuous biosensing as a potential microfluidic device for measuring the level of inflammatory responses. The detail design strategies and experimental demonstrations will be given throughout the talk. As a concluding remark, the potential applications of the technologies developed as well as the impact on current clinical issues will be also discussed.
Key words: Blood Separation, Microfluidic Devices, Continuous Real Time, CPB
문의: Prof. Je-Kyun Park (4315)
- 아 래 -
1) 제목 : Microfluidic Devices for Continuous Real Time Blood Plasma Separation and
Analysis
2) 연사 : Dr. Sung Yang
3) 소속 : Department of Bioengineering, The Pennsylvania State University,
University Park, PA, USA
4) 일시 : 2006. 7. 14 (Fri) 16:10-17:30
5) 장소 : Room 219, Chung Moon Soul Building (E16)
<Abstract>:
It is well known that that cardiac surgery induces systemic inflammatory responses,
particularly when cardiopulmonary bypass (CPB) procedure is used. These systemic responses are attributed to several factors, including exposure of blood to nonphysiologic surfaces of the heart-lung circuit, ischemia-reperfusion of the involved tissues, surgical trauma and hypothermia. Currently, there is no effective method to prevent this systemic inflammatory response syndrome in patients undergoing CPB. The ability to clinically intervene in inflammation, or even study the inflammatory response to CPB, is limited by the lack of timely measurements of inflammatory responses. Thus, there is a need for a microanalytical system, which can separate blood plasma from whole blood and measure the concentration of the clinically relevant proteins in continuous, real time while the surgery is proceeding.
The goal of this study was to achieve core technologies for the development of a microanalytical system, which can separate blood plasma from blood and measure inflammatory responses in continuous, real time while cardiac surgery is operating. Thus, two independent microfluidic devices are introduced throughout the talk. One is a microfluidic device for continuous, real time blood plasma separation from blood. Second is a microfluidic device for continuous biosensing as a potential microfluidic device for measuring the level of inflammatory responses. The detail design strategies and experimental demonstrations will be given throughout the talk. As a concluding remark, the potential applications of the technologies developed as well as the impact on current clinical issues will be also discussed.
Key words: Blood Separation, Microfluidic Devices, Continuous Real Time, CPB
문의: Prof. Je-Kyun Park (4315)
